The homeostatic properties of the mannose receptor in health and disease
نویسنده
چکیده
RESUMEN El estudio de la especificidad y distribución anatómica del Receptor de la Manosa (MR) y la caracterización fenotípica de ratones deficientes en el MR han permitido discernir la función de este receptor en condiciones fisiológicas normales y patológicas. En esta revisión se considera la biología del MR en tres contextos diferentes: A nivel molecular como miembro de la familia de receptores de manosa; como receptor de macrófagos y células dendríticas; y como un marcador de vasos linfáticos. Resultados recientes en estas tres áreas resaltan las propiedades únicas de este receptor y la necesidad de mantener la mente abierta a la hora de establecer su función fisiológica.
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